diff --git a/pkgs/development/ruby-modules/gem-config/default.nix b/pkgs/development/ruby-modules/gem-config/default.nix
index 1a09ce60c044..5f054e6b9962 100644
--- a/pkgs/development/ruby-modules/gem-config/default.nix
+++ b/pkgs/development/ruby-modules/gem-config/default.nix
@@ -528,6 +528,14 @@ in
       "--with-libvirt-include=${libvirt}/include"
       "--with-libvirt-lib=${libvirt}/lib"
     ];
+    dontBuild = false;
+    postPatch = ''
+      # https://gitlab.com/libvirt/libvirt-ruby/-/commit/43543991832c9623c00395092bcfb9e178243ba4
+      substituteInPlace ext/libvirt/common.c \
+        --replace 'st.h' 'ruby/st.h'
+      substituteInPlace ext/libvirt/domain.c \
+        --replace 'st.h' 'ruby/st.h'
+    '';
   };
 
   ruby-lxc = attrs: {